This link is maybe on the most importan you could ever read about the eradication of malaria.
First article found:
In the United States, the National Malaria Eradication Program (NMEP) was launched on 1 July 1947. This federal program — with state and local participation — had succeeded in eradicating malaria in the United States by 1951.
Endemic malaria in the United States, 1934-35.Prior to the establishment of the NMEP, malaria had beenendemic across much of the United States. By the 1930s, it had become concentrated in 13 southeastern states. (For example, in the Tennessee River Valley it had a prevalence of about 30% in 1933.)
A national malaria eradication effort was originally proposed byLouis Laval Williams. The NMEP was directed by the federal Communicable Disease Center (now the Centers for Disease Control and Prevention, or CDC ) created in 1946 and based inAtlanta, Georgia. It was a cooperative undertaking by federal, state and local health agencies. The Program had evolved from the Office of Malaria Control in War Areas, which had been created in 1942 to suppress malaria near military bases in the United States during World War II. The CDC’s first director –Justin M. Andrews -- was also Georgia’s chief malariologist.
The new agency was a branch of the U.S. Public Health Service and Atlanta was chosen as its headquarters because malaria was locally endemic. Offices were located on the sixth floor of the Volunteer Building on Peachtree Street. With an annual budget of about $1 million, some 59% of its personnel were engaged in mosquito abatement and habitat control. Among its 369 employees, the main jobs at CDC at this time were entomology and engineering. In 1946, there were only seven medical officers on duty and an early organization chart was drawn, somewhat fancifully, in the shape of a mosquito.
During the CDC's first few years, more than 6,500,000 homes were sprayed with the insecticide DDT. DDT was applied to the interior surfaces of rural homes or entire premises in counties where malaria was reported to have been prevalent in recent years. In addition, wetland drainage, removal of mosquito breeding sites, and DDT spraying (occasionally from aircraft) were all pursued. In 1947, some 15,000 malaria cases were reported. By the end of 1949, over 4,650,000 housespray applications had been made and the United States was declared free of malaria as a significant public health problem. By 1950, only 2,000 cases were reported. By 1951, malaria was considered eliminated altogether from the country and the CDC gradually withdrew from active participation in the operational phases of the program, shifting its interest to surveillance. In 1952, CDC participation in eradication operations ceased altogether.
A major international effort along the lines of the NMEP — the Global Malaria Eradication Programme (1955–1969), administered by the World Health Organization — was unsuccessful.
"Florida has its own history with malaria. In 1887, fear of malaria was so intense that most life insurance companies would not insure anyone south of Jacksonville. Workers attempting to build a canal across Florida in the 1900s were stopped by armies of malaria-carrying mosquitos. When malaria besieged the town of Perry, southeast of Tallahassee, in 1920, the state board of health and U.S. Public Health service developed a comprehensive mosquito control strategy still used today. They drained swamps, deployed mosquito larva-eating Gambusia minnows, and installed window screens on the houses. In 1922, the Florida Anti-Mosquito Association (FAMA) formed to continue the bug war. Florida saw its last native case of malaria in 1948. FAMA now continues its work as the Florida Mosquito Control Association (floridamosquito.org)."